Expresión de búsqueda:
HISTAMINE H1 ANTAGONISTS, NON-SEDATING
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Histamine H1 Antagonists, Non-Sedating
Descriptor
Español
:
Antagonistas de los Receptores Histamínicos H1 no Sedantes
Descriptor
Portugués
:
Antagonistas dos Receptores Histamínicos H1 não Sedativos
Categoría:
D27.505.519.625.375.425.400.500
D27.505.696.577.375.425.400.500
Definición
Inglés
:
A class of non-sedating drugs that bind to but do not activate
histamine
receptors (
DRUG INVERSE AGONISM
), thereby blocking the actions of
histamine
or
histamine agonists
. These
antihistamines
represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and
metabolism
. Compared to the early (first generation)
antihistamines
, these non-sedating
antihistamines
have greater receptor specificity, lower penetration of
BLOOD-BRAIN BARRIER
, and are less likely to cause
drowsiness
or
psychomotor impairment.
Relacionados
Inglés
:
Anti-Allergic Agents
Nota Histórica
Inglés
:
2003
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Número del Registro:
37547
Identificador Único:
D039563
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS